RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-27a
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
rattus norvegicus
Detection Methods
PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
RETINOID X RECEPTOR ALPHA
Pathway
NA
PubMed ID
Title
Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation
Year
2009
Function
"Downregulation of mirnas mir-27a and 27b transforms activated rat hsc into a resting hsc phenotype, reducing cell proliferation and fat accumulation."